Welcome to PEARC20! PEARC20’s theme is “Catch the Wave.” This year’s theme embodies the spirit of the community’s drive to stay on pace and in front of all the new waves in technology, analytics, and a globally connected and diverse workforce. We look forward to this year’s PEARC20 virtual meeting, where we can share scientific discovery and craft the future infrastructure.
The conference will be held in Pacific Time (PT) and the times listed below are in Pacific Time.
The connection information for all PEARC20 workshops, tutorials, plenaries, track presentations, BOFs, Posters, Visualization Showcase, and other affiliated events, are in the PEARC20 virtual conference platform, Brella. If you have issues joining Brella, please email pearcinfo@googlegroups.com.
There has been a rapid development in genome sequencing, including high-throughput next generation sequencing (NGS) technologies, automation in biological experiments, new bioinformatics tools and utilization of high-performance computing and cloud computing. ChIP-based NGS technologies, e.g. ChIP-seq and ChIP-exo, are widely used to detect the binding sites of DNA-interacting proteins in the genome and help us to have a deeper mechanistic understanding of genomic regulation. As sequencing data is generated at an unprecedented pace from the ChIP-based NGS pipelines, there is an urgent need for a metadata management system. To meet this need, we developed the Platform for Eukaryotic Genomic Regulation (PEGR), a web service platform that logs metadata for samples and sequencing experiments, manages the data processing workflows, and provides reporting and visualization. PEGR links together people, samples, protocols, DNA sequencers and bioinformatics computation. With the help of PEGR, scientists can have a more integrated understanding of the sequencing data and better understand the scientific mechanisms of genomic regulation. In this paper, we present the architecture and the major functionalities of PEGR. We also share our experience in developing this application and discuss the future directions.
